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Introducing PathExplore™ Fibrosis

Unlock the fibrotic microenvironment directly from H&E whole slide images. 

- Characterize the collagen & fiber composition of the tumor microenvironment to fuel oncology research for novel drug development 

- Quantify fiber morphological features with high spatial specificity

- Integrate fibrosis quantification with immune and other TME characteristics quantified in PathExplore™

Fibers, collagen, and fibrosis are emerging biomarkers for oncology

The search for novel biomarkers for oncology and fibrosis has led to increased interest in studying fibers, particularly fibrosis and collagen fibers, because these structural elements of the tumor microenvironment (TME) play significant roles in cancer progression, metastasis, immune response, and drug resistance.

Studying fibrosis and collagen fibers in cancer research is challenging because traditional methods:

  • Are labor-intensive
  • Require specialized stains and equipment, and access to tissue
  • Are challenging to use at scale

 

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PathExplore™ Fibrosis

Quantify the fibrotic microenvironment  

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Capture and analyze fibrosis, collagen, and fiber directly from routine pathology slides

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Fast & Scalable Fibrotic Microenvironment Analysis

Unlike traditional methods that require special stains and complex imaging technology, PathExplore™ Fibrosis leverages AI to quickly analyze routine H&E-stained slides, enabling large-scale studies and fast biomarker discovery.

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Quantitative Insights

The measurement of fibrosis, collagen, and fiber morphology directly from whole-slide images provides an unprecedented level of detail on tumor microenvironment features, offering new opportunities to explore tumor biology and therapeutic responses.

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Integrate with Standard Pathology Workflows

By working with standard pathology workflows (H&E-stained slides), the algorithm democratizes advanced fibrosis analysis, allowing labs to integrate it easily without additional microscopy equipment or complex preparation techniques.

Access PathExplore™ Fibrosis today

See for Yourself

-  Try our self-serve demo for hands-on experience.

Deploy on your slides 

- Access PathExplore™ Fibrosis by reaching out at bd@pathai.com 

Our content library

CASE STUDY

AI-Assisted Titer Selection in Early Assay Development

  • PathAI deployed IHC Explore on prostate cancer specimens stained with a novel, in-development assay
  • IHC Explore quantifies staining intensity at single-cell resolution, enabling rapid assay characterization and titer optimization​
  • Continuous staining intensity measurement provides added value for next-generation biomarkers and precision medicine strategies

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Publication Collections

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2-Aug-19-2024-04-55-00-7858-PM
3-Aug-19-2024-04-55-00-7879-PM

PathExplore™ and PathExplore™ Fibrosis are for research use only. Not for use in diagnostic procedures.